R&D

Research Institute Introduction

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Innovating Health
Bridging Science
Daehan Nupharm’s research institutes consist of the Central Research Institute, Bio Research Institute, and VET Lab, working closely together based on their respective expertise.
Bio Research Institute
The Daehan Nupharm Bio Research Institute is strengthening its research capabilities through the adoption of advanced technologies and collaboration, aiming to develop globally competitive biopharmaceuticals.

In the post-COVID era, demand for treatments for various modern diseases is rapidly increasing. In response to these changes, the Bio Research Institute is leading the development of next-generation therapies to address unmet medical needs through continuous innovation and convergence. We have secured essential core technologies for next-generation biopharmaceutical R&D, including AI drug design, cell and nucleic acid therapeutics, and protein engineering, and are expanding our R&D pipeline in multiple directions. The Bio Research Institute will continue to grow as a center for developing next-generation therapies that resolve unmet medical needs through ongoing technological innovation and integration.

Research Fields
  • Peptide drug
    Peptide Drug
  • Recombinant protein drug
    Recombinant Protein Drug
  • Epigenome editing therapy
    Epigenome Editing–based Therapeutics
  • Stem cell therapy
    (Companion animals)
    Stem Cell Therapeutics
Peptide drug
Peptide Drug Research
The peptide research team is developing peptide-based therapeutics to combat infectious diseases caused by a wide range of viruses.
By targeting viral lipid membranes—found in most viruses—they are working on antiviral peptides applicable to multiple viral infections.
This therapeutic strategy of directly disrupting viral membranes represents a new approach to potential future viral epidemics.
Recombinant protein drug
Recombinant Protein Drug Research
The protein drug team conducts research based on recombinant proteins to develop new treatments.
Targeting cancer, metabolic diseases, immune disorders, dementia, and more, they discover novel drug candidates using 3D protein structures and AI technology, and carry out optimization and engineering studies.
Epigenome editing therapy
Epigenome Editing–based Therapeutics Research
The epigenome editing team is developing therapeutics that regulate gene expression without altering genetic sequences.
Epigenetic therapeutics can control the expression of disease-related genes without direct genetic mutations. Since existing approaches have limitations for infectious, metabolic, and neurological diseases, the team is working on therapies that act specifically on target genes to meet these new medical needs.
Stem cell therapy
Stem Cell Therapeutics Research
The stem cell research team aims to develop veterinary cell therapies, using technologies to manipulate and culture living cells outside the body.
To respond proactively to the rapidly growing companion animal Health market, they have established a dedicated R&D team to develop stem cell therapeutics for pets. We have entered outdoor clinical trial stages in Korea and are preparing for the nation’s first commercialized stem cell therapy for companion animals.
  • STEP 01
    Adipose Tissue
    Sampling
  • STEP 02
    Stem Cell
    Isolation
  • STEP 03
    Stem Cell
    Culture
  • STEP 04
    Nitrogen Tank
    Storage
  • STEP 05
    Administration
Research Capabilities
  • AI-based Drug Design Platform
    Technology to design optimized drug candidates for target proteins based on 3D protein structures and predictive algorithms.
  • High-throughput Candidate Screening Technology
    Establishes efficient, large-scale screening methods such as ELISA and BLI for drug candidates.
  • Biopharmaceutical Process Development Technology
    Holds optimized production and purification technologies for biopharmaceuticals across different platforms.
  • Multi-target Antibody Design Technology
    Possesses antibody design technology capable of targeting two or more molecules simultaneously.
  • Cell and Nucleic Acid Therapeutics Platforms
    Equipped with development platforms for cell-based and mRNA nucleic acid–based drugs.
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