대한뉴팜

Daehan New Pharm launched ‘DH Luthione Injection,’ a glutathione (GSH, glutathione sulfhydryl) drug recognized for its powerful antioxidant function, detoxification, and immune-enhancing effects.

Glutathione is a small protein composed of three amino acids—cysteine, glutamic acid, and glycine—produced mainly in animal cells, especially in the liver. Its primary functions include antioxidation, detoxification, immune system enhancement, and anti-inflammatory effects. Other antioxidants such as vitamins C and E depend on glutathione, making it the most potent antioxidant known.

In industrial animals, glutathione’s functions can prevent productivity loss caused by various stresses and frequent drug exposure, supporting its long-term use in livestock.

However, most glutathione products approved for animals are oral formulations, which show low bioavailability due to poor absorption, limiting their effectiveness. Particularly during vaccinations such as foot-and-mouth disease, there was a need to develop injectable formulations that maximize stress relief, reduce inflammation, and boost immunity.

To maximize effects, Daehan New Pharm used the same formulation and high-quality raw materials (from Kyowa Hakko Bio Co., Ltd.) as its leading human glutathione injection ‘Luthione Injection’ to develop ‘DH Luthione,’ the first freeze-dried glutathione injectable for animals.

Clinical trials at Gyeongsang National University Veterinary College demonstrated that ‘DH Luthione’ effectively reduced stress and inflammation markers (cortisol, TNF-α, CRP) after foot-and-mouth disease vaccination. It significantly increased cell-mediated immunity (IFN-γ) and humoral immunity markers (IgG, IgM, IgA), and improved liver function markers (AST, ALT, bilirubin) while raising albumin levels.

These verified benefits make ‘DH Luthione’ a valuable agent for enhancing productivity in industrial animals.