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Launch of triple combination drug for hypertension and hyperlipidemia ‘Avatri Tablet’
2021.02.05

Daehan New Pharm has launched “Avatri Tablet,” the first triple combination drug in Korea containing atorvastatin, amlodipine, and valsartan.

 

Avatri Tablet is designed to offer enhanced medication convenience for patients with hypertension and dyslipidemia. According to data from the Health Insurance Review and Assessment Service (HIRA), about 31.9% of hypertensive patients receive concurrent treatment for dyslipidemia, and the number of such comorbid cases is rapidly increasing. Combination therapies such as Avatri are known to improve long-term treatment adherence in hypertension and dyslipidemia management.

 

Compared with patients taking separate medications, those on fixed-dose combination therapies had a 117% lower risk of discontinuation, with an average treatment duration of 35 months versus 7 months for separate dosing. Additionally, the UMPIRE study confirmed that fixed-dose combination therapy improves medication adherence by 33%.

 

The efficacy of Avatri Tablet in controlling seated systolic blood pressure (siSBP) and low-density lipoprotein cholesterol (LDL-C) was verified through clinical trials. After eight weeks of administration, the Avatri group showed a 22.75 mmHg reduction in siSBP, compared to a 5.4 mmHg reduction in the valsartan/atorvastatin comparator group.

 

In lipid control, Avatri also demonstrated remarkable results. After eight weeks, the Avatri -treated group showed a 47.15% reduction in LDL-C, whereas the control group receiving amlodipine/valsartan showed an increase in LDL-C levels.

 

By combining three active ingredients to treat two diseases, Avatri provides effective regulation of lipid and blood pressure levels, making it highly beneficial for preventing cardiovascular diseases in hypertensive patients with dyslipidemia who require intensive treatment and management. The company stated that Avatri has strong potential for development in various forms, including those aimed at improving medication adherence, and reaffirmed its commitment to developing improved new drugs with superior therapeutic efficacy.
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Customer Service Department: IT Team, Management Information Division
Personal Information Manager: Park Kangwon
Phone No.: +82-31-778-2626
Email: webmaster@dhnp.co.kr

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1. Personal Information Infringement Report Center (www.1336.or.kr/ No area code 118)
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